Israeli Study Finds Mankai Reduces Post-Meal Blood Sugar in Diabetes Patients

A groundbreaking clinical trial conducted in Israel has shown that Mankai, a cultivated aquatic plant, can significantly reduce post-meal blood sugar levels in patients with type 2 diabetes. The study, led by researchers from Sheba Medical Center and Ben-Gurion University of the Negev, found that consuming a Mankai-based beverage after dinner resulted in a 20% reduction in blood sugar levels, with effects comparable to some diabetes medications.

The trial involved 45 participants with type 2 diabetes, who were randomly assigned to drink either 300 ml of Mankai or water after dinner for two weeks, followed by a switch in interventions for another two weeks. Continuous glucose monitoring and laboratory tests were used to track blood sugar levels throughout the study. The results, published in Obesity, Diabetes, and Metabolism, revealed that Mankai not only lowered peak sugar levels but also accelerated the return to baseline levels.

Often described as the world’s smallest flowering plant (0.1–0.2 mm in diameter), Mankai belongs to the duckweed family, specifically Wolffia globosa. It is grown in controlled water-based environments rather than in the wild. Historically, Mankai has been used as a traditional food source in Thailand, where it is known as Pham, due to its high protein content.

Mankai is also rich in dietary fiber and antioxidants and has been previously recognized for its health benefits, including improving vascular and brain health and reducing abdominal fat. The recent findings suggest that Mankai could offer a new dietary approach for managing diabetes, complementing existing treatments.

Prof. Iris Shai said the results “highlight the potential of Mankai as a valuable tool for diabetes management” and emphasized the need for further investigation.

Dr. Gal Tsaban noted that the study “introduces a promising new option for managing diabetes and reducing associated complications.”

“Nutrition plays a crucial role in both the development and management of diabetes,” added Prof. Amir Tirosh. “Incorporating Mankai into the diet can enhance blood sugar control and provide beneficial nutrients that support overall health.”

The work was supported by grants from the German Research Foundation (DFG) and the Israeli Health and Science and Technology ministries.